2021 Big 12 Conference Leaders Turnover Margin - Games in August/September Only through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma | 4 | 5 | 3 | 8 | 0 | 3 | 3 | 5 | 1.25 |
| 2 | TCU | 3 | 1 | 4 | 5 | 1 | 2 | 3 | 2 | 0.67 |
| 3 | Baylor | 4 | 2 | 4 | 6 | 4 | 0 | 4 | 2 | 0.50 |
| 3 | Kansas | 4 | 4 | 1 | 5 | 1 | 2 | 3 | 2 | 0.50 |
| 3 | Texas | 4 | 2 | 3 | 5 | 1 | 2 | 3 | 2 | 0.50 |
| 6 | Oklahoma State | 4 | 4 | 2 | 6 | 3 | 2 | 5 | 1 | 0.25 |
| 7 | Kansas State | 4 | 2 | 4 | 6 | 3 | 4 | 7 | -1 | -0.25 |
| 8 | Texas Tech | 4 | 0 | 6 | 6 | 4 | 4 | 8 | -2 | -0.50 |
| 8 | Iowa State | 4 | 1 | 3 | 4 | 2 | 4 | 6 | -2 | -0.50 |
| 10 | West Virginia | 4 | 1 | 1 | 2 | 4 | 4 | 8 | -6 | -1.50 |