2021 Big 12 Conference Leaders Rushing Offense - Games in October Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | TCU | 5 | 200 | 1051 | 5.26 | 8 | 40.00 | 210.20 |
| 2 | Oklahoma | 5 | 162 | 985 | 6.08 | 12 | 32.40 | 197.00 |
| 3 | Oklahoma State | 4 | 187 | 838 | 4.48 | 6 | 46.75 | 209.50 |
| 4 | Baylor | 4 | 151 | 812 | 5.38 | 11 | 37.75 | 203.00 |
| 4 | Texas Tech | 5 | 178 | 812 | 4.56 | 14 | 35.60 | 162.40 |
| 6 | Iowa State | 4 | 135 | 806 | 5.97 | 9 | 33.75 | 201.50 |
| 7 | Texas | 4 | 142 | 640 | 4.51 | 6 | 35.50 | 160.00 |
| 8 | Kansas | 4 | 152 | 585 | 3.85 | 3 | 38.00 | 146.25 |
| 9 | West Virginia | 4 | 135 | 535 | 3.96 | 7 | 33.75 | 133.75 |
| 10 | Kansas State | 4 | 123 | 453 | 3.68 | 6 | 30.75 | 113.25 |