2021 Big 12 Conference Leaders Total Offense - Games in October Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | TCU | 5 | 1051 | 1060 | 322 | 2111 | 6.56 | 422.2 |
| 2 | Oklahoma | 5 | 985 | 1526 | 308 | 2511 | 8.15 | 502.2 |
| 3 | Oklahoma State | 4 | 838 | 828 | 299 | 1666 | 5.57 | 416.5 |
| 4 | Baylor | 4 | 812 | 954 | 269 | 1766 | 6.57 | 441.5 |
| 4 | Texas Tech | 5 | 812 | 1221 | 332 | 2033 | 6.12 | 406.6 |
| 6 | Iowa State | 4 | 806 | 974 | 247 | 1780 | 7.21 | 445.0 |
| 7 | Texas | 4 | 640 | 989 | 263 | 1629 | 6.19 | 407.3 |
| 8 | Kansas | 4 | 585 | 545 | 243 | 1130 | 4.65 | 282.5 |
| 9 | West Virginia | 4 | 535 | 1230 | 283 | 1765 | 6.24 | 441.3 |
| 10 | Kansas State | 4 | 453 | 1074 | 238 | 1527 | 6.42 | 381.8 |