2021 Big 12 Conference Leaders Total Offense - Games in November Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | TCU | 4 | 685 | 1052 | 260 | 1737 | 6.68 | 434.3 |
| 2 | Iowa State | 4 | 594 | 1229 | 280 | 1823 | 6.51 | 455.8 |
| 3 | Kansas State | 4 | 736 | 618 | 215 | 1354 | 6.30 | 338.5 |
| 4 | Texas Tech | 3 | 356 | 674 | 178 | 1030 | 5.79 | 343.3 |
| 5 | Oklahoma State | 4 | 878 | 870 | 303 | 1748 | 5.77 | 437.0 |
| 6 | Texas | 4 | 680 | 837 | 271 | 1517 | 5.60 | 379.3 |
| 7 | Baylor | 4 | 830 | 798 | 291 | 1628 | 5.59 | 407.0 |
| 8 | Kansas | 4 | 517 | 892 | 253 | 1409 | 5.57 | 352.3 |
| 9 | Oklahoma | 3 | 475 | 526 | 189 | 1001 | 5.30 | 333.7 |
| 10 | West Virginia | 4 | 513 | 860 | 287 | 1373 | 4.78 | 343.3 |