2021 Big 12 Conference Leaders Rushing Offense - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 10 | 448 | 1919 | 4.28 | 21 | 44.80 | 191.90 |
| 2 | Baylor | 11 | 437 | 2110 | 4.83 | 18 | 39.73 | 191.82 |
| 3 | TCU | 10 | 405 | 2007 | 4.96 | 16 | 40.50 | 200.70 |
| 4 | West Virginia | 12 | 397 | 1409 | 3.55 | 14 | 33.08 | 117.42 |
| 5 | Oklahoma | 11 | 375 | 2033 | 5.42 | 21 | 34.09 | 184.82 |
| 6 | Texas | 10 | 374 | 1794 | 4.80 | 17 | 37.40 | 179.40 |
| 7 | Kansas | 10 | 356 | 1418 | 3.98 | 12 | 35.60 | 141.80 |
| 8 | Texas Tech | 10 | 343 | 1556 | 4.54 | 22 | 34.30 | 155.60 |
| 9 | Iowa State | 11 | 340 | 1769 | 5.20 | 21 | 30.91 | 160.82 |
| 10 | Kansas State | 11 | 339 | 1634 | 4.82 | 21 | 30.82 | 148.55 |