2021 Big 12 Conference Leaders Rushing Offense - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas | 2 | 83 | 597 | 7.19 | 8 | 41.50 | 298.50 |
| 2 | Baylor | 2 | 92 | 547 | 5.95 | 6 | 46.00 | 273.50 |
| 3 | Kansas State | 1 | 48 | 269 | 5.60 | 4 | 48.00 | 269.00 |
| 4 | Oklahoma State | 3 | 144 | 616 | 4.28 | 4 | 48.00 | 205.33 |
| 5 | Iowa State | 1 | 37 | 184 | 4.97 | 3 | 37.00 | 184.00 |
| 6 | Kansas | 1 | 38 | 172 | 4.53 | 3 | 38.00 | 172.00 |
| 7 | TCU | 1 | 30 | 170 | 5.67 | 1 | 30.00 | 170.00 |
| 8 | Texas Tech | 2 | 65 | 322 | 4.95 | 5 | 32.50 | 161.00 |
| 9 | Oklahoma | 1 | 35 | 116 | 3.31 | 3 | 35.00 | 116.00 |