2021 Mountain West Conference Leaders Long All Purpose Plays - Games vs. FBS Teams With Winning Record Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Dae Dae Hunter | Hawai'i | SO | RB | 5 | 3 | 2 | 2 | 2 | 2 | 1 | 0 |
| 1 | Charles Williams | UNLV | SR | RB | 8 | 4 | 3 | 3 | 2 | 2 | 0 | 0 |
| 3 | Jordan Byrd | SDSU | SR | RB | 7 | 3 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Stefan Cobbs | Boise St | JR | WR | 7 | 5 | 2 | 2 | 2 | 1 | 1 | 0 |
| 3 | Tyleek Collins | UNLV | SR | WR | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | Steve Jenkins | UNLV | JR | WR | 8 | 4 | 3 | 2 | 2 | 1 | 1 | 0 |
| 3 | Tyric LeBeauf | Boise St | JR | CB | 7 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Isaiah Neyor | Wyoming | SO | WR | 5 | 7 | 2 | 1 | 1 | 1 | 0 | 0 |
| 3 | Thomas Pannunzio | CSU | SR | WR | 7 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Cameron Stone | Wyoming | SO | CB | 5 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Titus Swen | Wyoming | JR | RB | 5 | 2 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Deven Thompkins | Utah State | SR | WR | 7 | 7 | 4 | 2 | 2 | 1 | 0 | 0 |
| 3 | Xazavian Valladay | Wyoming | SR | RB | 5 | 3 | 2 | 1 | 1 | 1 | 0 | 0 |