2021 Mountain West Conference Leaders Passes Defended - Games in August/September Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | New Mexico | 4 | 6 | 21 | 27 | 6.75 |
| 1 | Hawai'i | 5 | 4 | 23 | 27 | 5.40 |
| 3 | San Diego State | 4 | 6 | 19 | 25 | 6.25 |
| 3 | San Jose State | 4 | 0 | 25 | 25 | 6.25 |
| 5 | Fresno State | 5 | 1 | 23 | 24 | 4.80 |
| 6 | Boise State | 4 | 7 | 16 | 23 | 5.75 |
| 7 | Air Force | 4 | 3 | 16 | 19 | 4.75 |
| 8 | Wyoming | 4 | 6 | 12 | 18 | 4.50 |
| 8 | Utah State | 4 | 4 | 14 | 18 | 4.50 |
| 10 | Colorado State | 4 | 1 | 10 | 11 | 2.75 |
| 11 | Nevada | 3 | 1 | 9 | 10 | 3.33 |
| 12 | UNLV | 4 | 4 | 5 | 9 | 2.25 |