2021 Atlantic Coast Conference Leaders Interceptions - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Kei'Trel Clark | Louisville | SO | DB | 6 | 3 | 2 | 0 | 0.50 |
| 1 | Brandon Sebastian | BC | SR | DB | 6 | 3 | 0 | 0 | 0.50 |
| 1 | Jammie Robinson | FSU | SO | DB | 8 | 3 | 30 | 0 | 0.38 |
| 1 | Jermaine Waller | Va Tech | JR | DB | 9 | 3 | 41 | 0 | 0.33 |
| 1 | Traveon Redd | Wk Forest | SR | DB | 11 | 3 | 83 | 1 | 0.27 |
| 1 | John Petrishen | Pittsburgh | SR | LB | 11 | 3 | 35 | 1 | 0.27 |
| 7 | Trey Franklin | Louisville | SO | DB | 7 | 2 | 32 | 0 | 0.29 |
| 7 | Joey Blount | Virginia | SR | FS | 7 | 2 | 27 | 0 | 0.29 |
| 7 | Andrew Booth Jr. | Clemson | JR | CB | 7 | 2 | 0 | 0 | 0.29 |
| 7 | Jarvis Brownlee, Jr. | FSU | FR | DB | 8 | 2 | 70 | 1 | 0.25 |
| 7 | Darian Chestnut | Syracuse | FR | DB | 8 | 2 | 23 | 0 | 0.25 |
| 7 | Mario Goodrich | Clemson | SR | CB | 8 | 2 | 20 | 1 | 0.25 |
| 7 | Charlie Thomas | Ga Tech | JR | LB | 8 | 2 | 0 | 0 | 0.25 |
| 7 | Ja'Qurious Conley | N Carolina | SO | DB | 8 | 2 | 0 | 0 | 0.25 |
| 7 | Josh DeBerry | BC | JR | DB | 8 | 2 | -7 | 0 | 0.25 |
| 7 | R.J. Mickens | Clemson | SO | S | 9 | 2 | 37 | 0 | 0.22 |
| 7 | Jeremiah Lewis | Duke | JR | CB | 9 | 2 | 35 | 0 | 0.22 |
| 7 | Leonard Johnson | Duke | SR | CB | 9 | 2 | 30 | 0 | 0.22 |
| 7 | Caelen Carson | Wk Forest | FR | DB | 9 | 2 | 30 | 0 | 0.22 |
| 7 | Cedric Gray | N Carolina | SO | LB | 9 | 2 | 21 | 0 | 0.22 |
| 7 | Jaiden Woodbey | BC | JR | DB | 9 | 2 | 12 | 0 | 0.22 |
| 7 | Cam'Ron Kelly | N Carolina | JR | DB | 9 | 2 | 3 | 0 | 0.22 |
| 7 | Drake Thomas | NC State | SO | LB | 10 | 2 | 0 | 1 | 0.20 |
| 7 | Ja'Sir Taylor | Wk Forest | SR | DB | 11 | 2 | 48 | 0 | 0.18 |
| 25 | Cyrus Fagan | NC State | SR | SAF | 2 | 1 | 16 | 0 | 0.50 |
| 25 | Bryan Bresee | Clemson | SO | DT | 2 | 1 | 0 | 0 | 0.50 |
| 25 | Avantae Williams | Miami (Fl) | FR | S | 4 | 1 | 32 | 0 | 0.25 |
| 25 | Nasir Greer | Wk Forest | JR | DB | 4 | 1 | 14 | 0 | 0.25 |
| 25 | Coby Davis | Wk Forest | JR | DB | 4 | 1 | 0 | 0 | 0.25 |
| 25 | Fentrell Cypress II | Virginia | SO | DB | 5 | 1 | 66 | 0 | 0.20 |
| 25 | Jahmin Muse | BC | SR | DB | 6 | 1 | 22 | 1 | 0.17 |
| 25 | Isaiah Moore | NC State | JR | LB | 6 | 1 | 1 | 0 | 0.17 |
| 25 | Nate Thompson | Duke | JR | S | 6 | 1 | 0 | 0 | 0.17 |
| 25 | Akeem Dent | FSU | SO | DB | 6 | 1 | 0 | 0 | 0.17 |
| 25 | Omarion Cooper | FSU | FR | DB | 6 | 1 | 0 | 0 | 0.17 |
| 25 | Amari Carter | Miami (Fl) | SR | S | 6 | 1 | 0 | 0 | 0.17 |
| 25 | James Williams | Miami (Fl) | FR | S | 6 | 1 | 0 | 0 | 0.17 |
| 25 | Kenderick Duncan | Louisville | JR | DB | 7 | 1 | 3 | 0 | 0.14 |
| 25 | Nolan Turner | Clemson | SR | S | 7 | 1 | 2 | 0 | 0.14 |
| 25 | Josh Minkins | Louisville | FR | DB | 7 | 1 | 2 | 0 | 0.14 |
| 25 | Travis Jay | FSU | FR | DB | 7 | 1 | 0 | 0 | 0.14 |
| 25 | De'Vante Cross | Virginia | SR | FS | 7 | 1 | 0 | 0 | 0.14 |
| 25 | Jaylin Alderman | Louisville | FR | LB | 8 | 1 | 66 | 1 | 0.13 |
| 25 | Jahfari Harvey | Miami (Fl) | FR | DL | 8 | 1 | 33 | 1 | 0.13 |
| 25 | Marvin Dallas | Louisville | JR | LB | 8 | 1 | 27 | 0 | 0.13 |
| 25 | Corey Flagg, Jr. | Miami (Fl) | FR | LB | 8 | 1 | 9 | 0 | 0.13 |
| 25 | Kyler McMichael | N Carolina | JR | DB | 8 | 1 | 9 | 0 | 0.13 |
| 25 | Tyler Venables | Clemson | SO | S | 8 | 1 | 7 | 0 | 0.13 |
| 25 | Tyler Baker-Williams | NC State | JR | NIC | 8 | 1 | 7 | 0 | 0.13 |
| 25 | Juanyeh Thomas | Ga Tech | JR | DB | 8 | 1 | 6 | 0 | 0.13 |