2021 Atlantic Coast Conference Leaders Passes Defended - Games in November Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Andrew Booth Jr. | Clemson | JR | CB | 3 | 3 | 3 | 6 | 2.00 |
| 1 | Jammie Robinson | FSU | SO | DB | 4 | 3 | 0 | 3 | 0.75 |
| 3 | Derrek Pitts, Jr. | NC State | SR | CB | 4 | 2 | 3 | 5 | 1.25 |
| 3 | Cam'Ron Kelly | N Carolina | JR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 3 | Anthony Johnson | Virginia | JR | DB | 3 | 2 | 1 | 3 | 1.00 |
| 3 | Malik Mustapha | Wk Forest | FR | DB | 4 | 2 | 1 | 3 | 0.75 |
| 7 | Omarion Cooper | FSU | FR | DB | 4 | 1 | 4 | 5 | 1.25 |
| 7 | Darian Chestnut | Syracuse | FR | DB | 3 | 1 | 3 | 4 | 1.33 |
| 7 | Shyheim Battle | NC State | FR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 7 | Dorian Strong | Va Tech | FR | DB | 4 | 1 | 3 | 4 | 1.00 |
| 7 | Kalen DeLoach | FSU | SO | LB | 4 | 1 | 2 | 3 | 0.75 |
| 7 | Akeem Dent | FSU | SO | DB | 4 | 1 | 2 | 3 | 0.75 |
| 7 | Tae Daley | Va Tech | SR | S | 4 | 1 | 2 | 3 | 0.75 |
| 7 | Ja'Sir Taylor | Wk Forest | SR | DB | 4 | 1 | 2 | 3 | 0.75 |
| 7 | Jaiden Woodbey | BC | JR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Mario Goodrich | Clemson | SR | CB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Sheridan Jones | Clemson | JR | CB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Jarvis Brownlee, Jr. | FSU | FR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Marcus Clarke | Miami (Fl) | FR | CB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Jeremiah Gemmel | N Carolina | SR | LB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Kyler McMichael | N Carolina | JR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Joshua Pierre-Louis | NC State | FR | NIC | 4 | 1 | 1 | 2 | 0.50 |
| 7 | M.J. Devonshire | Pittsburgh | SO | DB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | John Petrishen | Pittsburgh | SR | LB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Nick Andersen | Wk Forest | FR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 7 | Brandon Sebastian | BC | SR | DB | 2 | 1 | 0 | 1 | 0.50 |
| 7 | Tyler Baker-Williams | NC State | JR | NIC | 2 | 1 | 0 | 1 | 0.50 |
| 7 | Joey Blount | Virginia | SR | FS | 3 | 1 | 0 | 1 | 0.33 |
| 7 | R.J. Oben | Duke | SO | DE | 4 | 1 | 0 | 1 | 0.25 |
| 7 | Marvin Dallas | Louisville | JR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 7 | Avantae Williams | Miami (Fl) | FR | S | 4 | 1 | 0 | 1 | 0.25 |
| 7 | Drake Thomas | NC State | SO | LB | 4 | 1 | 0 | 1 | 0.25 |
| 7 | Phil Campbell III | Pittsburgh | SR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 7 | J.J. Roberts | Wk Forest | FR | DB | 4 | 1 | 0 | 1 | 0.25 |