2021 Atlantic Coast Conference Leaders Sacks Allowed - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Virginia Tech | 2 | 4.0 | 28 | 2.00 |
| 2 | North Carolina State | 2 | 5.0 | 41 | 2.50 |
| 3 | Duke | 2 | 8.0 | 55 | 4.00 |
| 4 | Clemson | 4 | 10.0 | 56 | 2.50 |
| 4 | Boston College | 3 | 10.0 | 73 | 3.33 |
| 4 | Pittsburgh | 3 | 10.0 | 89 | 3.33 |
| 7 | Louisville | 5 | 13.0 | 72 | 2.60 |
| 8 | Miami (Florida) | 4 | 14.0 | 85 | 3.50 |
| 9 | Syracuse | 4 | 15.0 | 88 | 3.75 |
| 9 | Georgia Tech | 4 | 15.0 | 140 | 3.75 |
| 11 | Wake Forest | 3 | 16.0 | 86 | 5.33 |
| 12 | North Carolina | 4 | 17.0 | 76 | 4.25 |
| 12 | Florida State | 4 | 17.0 | 125 | 4.25 |
| 14 | Virginia | 4 | 19.0 | 107 | 4.75 |