2021 Atlantic Coast Conference Leaders Rushing Offense - When Winning By 15+ Pts through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 4 | 69 | 428 | 6.20 | 3 | 72 | 18 | 9 | 5 |
| 2 | North Carolina | 3 | 60 | 291 | 4.85 | 3 | 62 | 16 | 8 | 1 |
| 3 | Miami (Florida) | 3 | 67 | 355 | 5.30 | 5 | 51 | 20 | 10 | 4 |
| 4 | Syracuse | 3 | 49 | 305 | 6.22 | 4 | 50 | 15 | 11 | 3 |
| 4 | Georgia Tech | 2 | 25 | 135 | 5.40 | 2 | 50 | 4 | 4 | 2 |
| 6 | Virginia Tech | 2 | 24 | 193 | 8.04 | 2 | 49 | 8 | 6 | 2 |
| 7 | Wake Forest | 7 | 145 | 535 | 3.69 | 5 | 48 | 26 | 13 | 3 |
| 8 | North Carolina State | 5 | 77 | 443 | 5.75 | 5 | 46 | 18 | 16 | 6 |
| 9 | Boston College | 3 | 51 | 211 | 4.14 | 3 | 41 | 12 | 5 | 1 |
| 10 | Virginia | 4 | 52 | 266 | 5.12 | 5 | 34 | 11 | 10 | 4 |
| 11 | Clemson | 4 | 91 | 412 | 4.53 | 5 | 30 | 24 | 9 | 1 |
| 12 | Duke | 3 | 49 | 217 | 4.43 | 1 | 26 | 11 | 6 | 1 |
| 13 | Pittsburgh | 8 | 158 | 695 | 4.40 | 11 | 25 | 39 | 24 | 2 |
| 13 | Florida State | 4 | 44 | 253 | 5.75 | 2 | 25 | 13 | 13 | 2 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||