2021 Atlantic Coast Conference Leaders Rushing Offense - When Losing By 15+ Pts through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Duke | 7 | 165 | 615 | 3.73 | 4 | 40 | 33 | 20 | 5 |
| 2 | Virginia Tech | 5 | 75 | 318 | 4.24 | 2 | 44 | 18 | 12 | 4 |
| 3 | Georgia Tech | 4 | 91 | 300 | 3.30 | 1 | 54 | 15 | 10 | 3 |
| 3 | Florida State | 4 | 31 | 228 | 7.35 | 3 | 75 | 10 | 7 | 3 |
| 3 | Syracuse | 3 | 47 | 141 | 3.00 | 1 | 48 | 11 | 10 | 3 |
| 6 | North Carolina | 5 | 47 | 232 | 4.94 | 2 | 63 | 11 | 8 | 2 |
| 6 | Virginia | 5 | 53 | 232 | 4.38 | 2 | 31 | 17 | 9 | 2 |
| 6 | Louisville | 3 | 47 | 207 | 4.40 | 3 | 29 | 11 | 6 | 2 |
| 9 | Miami (Florida) | 3 | 34 | 102 | 3.00 | 1 | 18 | 10 | 5 | 0 |
| 9 | Boston College | 4 | 38 | 53 | 1.39 | 2 | 17 | 6 | 2 | 0 |
| 9 | Wake Forest | 2 | 16 | 39 | 2.44 | 1 | 13 | 3 | 1 | 0 |
| 9 | Clemson | 1 | 3 | 23 | 7.67 | 1 | 10 | 1 | 1 | 0 |
| 9 | North Carolina State | 1 | 10 | -17 | -1.70 | 0 | 4 | 0 | 0 | 0 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||