2021 Atlantic Coast Conference Leaders Kickoff Returns - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Ret. | Yards | Avg. | TD | Ret./G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 2 | 4 | 209 | 52.25 | 1 | 2.0 | 104.5 |
| 1 | Duke | 2 | 14 | 323 | 23.07 | 1 | 7.0 | 161.5 |
| 3 | Wake Forest | 3 | 4 | 104 | 26.00 | 0 | 1.3 | 34.7 |
| 3 | Clemson | 4 | 7 | 170 | 24.29 | 0 | 1.8 | 42.5 |
| 3 | Florida State | 4 | 8 | 188 | 23.50 | 0 | 2.0 | 47.0 |
| 3 | Louisville | 5 | 16 | 357 | 22.31 | 0 | 3.2 | 71.4 |
| 3 | Georgia Tech | 4 | 10 | 217 | 21.70 | 0 | 2.5 | 54.3 |
| 3 | Virginia Tech | 2 | 9 | 187 | 20.78 | 0 | 4.5 | 93.5 |
| 3 | North Carolina | 4 | 8 | 166 | 20.75 | 0 | 2.0 | 41.5 |
| 3 | Syracuse | 4 | 15 | 298 | 19.87 | 0 | 3.8 | 74.5 |
| 3 | Virginia | 4 | 6 | 115 | 19.17 | 0 | 1.5 | 28.8 |
| 3 | Boston College | 3 | 5 | 79 | 15.80 | 0 | 1.7 | 26.3 |
| 3 | Miami (Florida) | 4 | 5 | 75 | 15.00 | 0 | 1.3 | 18.8 |
| 3 | Pittsburgh | 3 | 4 | 48 | 12.00 | 0 | 1.3 | 16.0 |