2021 Atlantic Coast Conference Leaders Turnover Margin - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 3 | 1 | 7 | 8 | 1 | 1 | 2 | 6 | 2.00 |
| 2 | Clemson | 4 | 5 | 2 | 7 | 2 | 5 | 7 | 0 | 0.00 |
| 2 | North Carolina | 4 | 1 | 3 | 4 | 1 | 3 | 4 | 0 | 0.00 |
| 2 | North Carolina State | 2 | 0 | 4 | 4 | 2 | 2 | 4 | 0 | 0.00 |
| 2 | Duke | 2 | 3 | 0 | 3 | 2 | 1 | 3 | 0 | 0.00 |
| 6 | Virginia Tech | 2 | 0 | 2 | 2 | 1 | 2 | 3 | -1 | -0.50 |
| 7 | Syracuse | 4 | 0 | 2 | 2 | 2 | 2 | 4 | -2 | -0.50 |
| 8 | Louisville | 5 | 1 | 1 | 2 | 3 | 3 | 6 | -4 | -0.80 |
| 8 | Virginia | 4 | 1 | 3 | 4 | 2 | 6 | 8 | -4 | -1.00 |
| 8 | Georgia Tech | 4 | 1 | 0 | 1 | 1 | 4 | 5 | -4 | -1.00 |
| 8 | Wake Forest | 3 | 3 | 3 | 6 | 2 | 8 | 10 | -4 | -1.33 |
| 12 | Florida State | 4 | 3 | 4 | 7 | 5 | 7 | 12 | -5 | -1.25 |
| 12 | Miami (Florida) | 4 | 1 | 2 | 3 | 3 | 5 | 8 | -5 | -1.25 |
| 14 | Boston College | 3 | 0 | 1 | 1 | 3 | 5 | 8 | -7 | -2.33 |