2021 Atlantic Coast Conference Leaders Turnover Margin - Games in August/September Only through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Wake Forest | 4 | 4 | 7 | 11 | 2 | 2 | 4 | 7 | 1.75 |
| 2 | Boston College | 4 | 1 | 6 | 7 | 2 | 2 | 4 | 3 | 0.75 |
| 3 | Virginia Tech | 4 | 1 | 5 | 6 | 1 | 2 | 3 | 3 | 0.75 |
| 3 | Duke | 4 | 2 | 5 | 7 | 5 | 2 | 7 | 0 | 0.00 |
| 3 | North Carolina State | 4 | 0 | 5 | 5 | 3 | 3 | 6 | -1 | -0.25 |
| 6 | Louisville | 4 | 1 | 4 | 5 | 2 | 2 | 4 | 1 | 0.25 |
| 7 | Clemson | 4 | 2 | 3 | 5 | 2 | 4 | 6 | -1 | -0.25 |
| 7 | Miami (Florida) | 5 | 1 | 3 | 4 | 3 | 4 | 7 | -3 | -0.60 |
| 7 | North Carolina | 4 | 2 | 3 | 5 | 4 | 4 | 8 | -3 | -0.75 |
| 10 | Georgia Tech | 4 | 6 | 2 | 8 | 2 | 1 | 3 | 5 | 1.25 |
| 10 | Pittsburgh | 4 | 4 | 2 | 6 | 4 | 1 | 5 | 1 | 0.25 |
| 10 | Virginia | 5 | 1 | 2 | 3 | 3 | 4 | 7 | -4 | -0.80 |
| 10 | Florida State | 4 | 2 | 2 | 4 | 3 | 8 | 11 | -7 | -1.75 |
| 14 | Syracuse | 4 | 2 | 1 | 3 | 2 | 3 | 5 | -2 | -0.50 |