2021 Atlantic Coast Conference Leaders Total Offense - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 1 | 252 | 455 | 82 | 707 | 8.62 | 707.0 |
| 2 | Clemson | 1 | 242 | 262 | 75 | 504 | 6.72 | 504.0 |
| 3 | Duke | 1 | 150 | 283 | 71 | 433 | 6.10 | 433.0 |
| 3 | Florida State | 1 | 199 | 133 | 71 | 332 | 4.68 | 332.0 |
| 5 | Miami (Florida) | 1 | 322 | 417 | 70 | 739 | 10.56 | 739.0 |
| 6 | North Carolina State | 1 | 218 | 287 | 68 | 505 | 7.43 | 505.0 |
| 7 | North Carolina | 1 | 305 | 214 | 67 | 519 | 7.75 | 519.0 |
| 8 | Syracuse | 1 | 286 | 337 | 66 | 623 | 9.44 | 623.0 |
| 9 | Boston College | 1 | 178 | 347 | 65 | 525 | 8.08 | 525.0 |
| 10 | Virginia | 1 | 206 | 339 | 64 | 545 | 8.52 | 545.0 |
| 10 | Louisville | 1 | 158 | 284 | 64 | 442 | 6.91 | 442.0 |
| 12 | Virginia Tech | 1 | 106 | 212 | 62 | 318 | 5.13 | 318.0 |
| 13 | Wake Forest | 1 | 161 | 252 | 60 | 413 | 6.88 | 413.0 |
| 14 | Georgia Tech | 1 | 158 | 254 | 59 | 412 | 6.98 | 412.0 |