2021 American Athletic Conference Leaders Opponent Penalties - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Tulsa | 4 | 33 | 293 | 8.3 | 73.3 |
| 2 | Tulane | 4 | 27 | 204 | 6.8 | 51.0 |
| 3 | South Florida | 4 | 23 | 219 | 5.8 | 54.8 |
| 4 | Navy | 3 | 21 | 198 | 7.0 | 66.0 |
| 5 | Cincinnati | 3 | 20 | 149 | 6.7 | 49.7 |
| 6 | East Carolina | 2 | 17 | 140 | 8.5 | 70.0 |
| 7 | SMU | 2 | 16 | 142 | 8.0 | 71.0 |
| 8 | Memphis | 1 | 11 | 122 | 11.0 | 122.0 |
| 9 | UCF | 1 | 9 | 74 | 9.0 | 74.0 |
| 10 | Temple | 2 | 7 | 67 | 3.5 | 33.5 |
| 11 | Houston | 1 | 6 | 40 | 6.0 | 40.0 |