2021 American Athletic Conference Leaders Sacks Allowed - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | UCF | 1 | 1.0 | 2 | 1.00 |
| 2 | Memphis | 1 | 2.0 | 12 | 2.00 |
| 3 | South Florida | 4 | 4.0 | 17 | 1.00 |
| 4 | Navy | 3 | 5.0 | 35 | 1.67 |
| 5 | SMU | 2 | 6.0 | 37 | 3.00 |
| 6 | Temple | 2 | 7.0 | 34 | 3.50 |
| 6 | East Carolina | 2 | 7.0 | 40 | 3.50 |
| 8 | Houston | 1 | 8.0 | 54 | 8.00 |
| 8 | Cincinnati | 3 | 8.0 | 58 | 2.67 |
| 10 | Tulsa | 4 | 10.0 | 72 | 2.50 |
| 11 | Tulane | 4 | 18.0 | 120 | 4.50 |