2021 American Athletic Conference Leaders Interceptions - All Games through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | East Carolina | 12 | 15 | 147 | 2 | 1.25 |
| 1 | Houston | 14 | 14 | 210 | 2 | 1.00 |
| 3 | Cincinnati | 14 | 19 | 214 | 1 | 1.36 |
| 3 | Tulsa | 13 | 11 | 115 | 1 | 0.85 |
| 3 | South Florida | 12 | 10 | 249 | 1 | 0.83 |
| 3 | Tulane | 12 | 10 | 156 | 1 | 0.83 |
| 3 | Temple | 12 | 6 | 56 | 1 | 0.50 |
| 8 | UCF | 13 | 11 | 114 | 0 | 0.85 |
| 8 | SMU | 12 | 10 | 120 | 0 | 0.83 |
| 8 | Memphis | 12 | 9 | 41 | 0 | 0.75 |
| 8 | Navy | 12 | 7 | 23 | 0 | 0.58 |