2021 American Athletic Conference Leaders Total Offense - Games Won Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tulane | 2 | 484 | 601 | 142 | 1085 | 7.64 | 542.5 |
| 2 | SMU | 8 | 1586 | 2723 | 632 | 4309 | 6.82 | 538.6 |
| 3 | East Carolina | 7 | 1466 | 2081 | 551 | 3547 | 6.44 | 506.7 |
| 4 | Tulsa | 7 | 1596 | 1807 | 546 | 3403 | 6.23 | 486.1 |
| 5 | South Florida | 2 | 666 | 268 | 166 | 934 | 5.63 | 467.0 |
| 6 | Memphis | 6 | 968 | 1824 | 421 | 2792 | 6.63 | 465.3 |
| 7 | Temple | 3 | 449 | 869 | 202 | 1318 | 6.52 | 439.3 |
| 8 | Houston | 12 | 1829 | 3378 | 827 | 5207 | 6.30 | 433.9 |
| 9 | UCF | 9 | 1913 | 1948 | 617 | 3861 | 6.26 | 429.0 |
| 10 | Cincinnati | 13 | 2343 | 3233 | 805 | 5576 | 6.93 | 428.9 |
| 11 | Navy | 4 | 1064 | 212 | 274 | 1276 | 4.66 | 319.0 |