2021 American Athletic Conference Leaders First Downs - Games Won Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Houston | 12 | 84 | 162 | 20 | 266 | 22.2 |
| 2 | Cincinnati | 13 | 116 | 134 | 15 | 265 | 20.4 |
| 3 | SMU | 8 | 85 | 130 | 12 | 227 | 28.4 |
| 4 | East Carolina | 7 | 72 | 91 | 11 | 174 | 24.9 |
| 4 | UCF | 9 | 93 | 91 | 10 | 194 | 21.6 |
| 6 | Tulsa | 7 | 82 | 80 | 17 | 179 | 25.6 |
| 7 | Memphis | 6 | 46 | 74 | 12 | 132 | 22.0 |
| 8 | Temple | 3 | 24 | 34 | 7 | 65 | 21.7 |
| 9 | Tulane | 2 | 27 | 22 | 2 | 51 | 25.5 |
| 10 | South Florida | 2 | 37 | 14 | 1 | 52 | 26.0 |
| 11 | Navy | 4 | 66 | 7 | 3 | 76 | 19.0 |