2021 American Athletic Conference Leaders Turnover Margin - Games Lost Only through 01/10/2022
| Name | G | Fum. Gain | Int. Gain | Total Gain | Fum. Lost | Int. Lost | Total Lost | Margin | Margin/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | South Florida | 10 | 6 | 8 | 14 | 7 | 12 | 19 | -5 | -0.50 |
| 2 | Tulane | 10 | 4 | 7 | 11 | 12 | 10 | 22 | -11 | -1.10 |
| 3 | Navy | 8 | 2 | 5 | 7 | 2 | 3 | 5 | 2 | 0.25 |
| 3 | East Carolina | 5 | 4 | 5 | 9 | 7 | 5 | 12 | -3 | -0.60 |
| 3 | Memphis | 6 | 1 | 5 | 6 | 6 | 8 | 14 | -8 | -1.33 |
| 6 | Tulsa | 6 | 3 | 4 | 7 | 4 | 8 | 12 | -5 | -0.83 |
| 6 | Temple | 9 | 5 | 4 | 9 | 11 | 9 | 20 | -11 | -1.22 |
| 8 | SMU | 4 | 1 | 3 | 4 | 3 | 4 | 7 | -3 | -0.75 |
| 9 | UCF | 4 | 3 | 2 | 5 | 3 | 4 | 7 | -2 | -0.50 |
| 10 | Cincinnati | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1.00 |
| 11 | Houston | 2 | 1 | 0 | 1 | 0 | 5 | 5 | -4 | -2.00 |