2021 American Athletic Conference Leaders Total Offense - Games in August/September Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | SMU | 4 | 929 | 1270 | 305 | 2199 | 7.21 | 549.8 |
| 2 | Tulsa | 4 | 751 | 1209 | 284 | 1960 | 6.90 | 490.0 |
| 3 | Memphis | 4 | 750 | 1170 | 265 | 1920 | 7.25 | 480.0 |
| 4 | Tulane | 4 | 623 | 1057 | 294 | 1680 | 5.71 | 420.0 |
| 5 | UCF | 3 | 757 | 903 | 235 | 1660 | 7.06 | 553.3 |
| 6 | East Carolina | 4 | 518 | 1080 | 278 | 1598 | 5.75 | 399.5 |
| 7 | Houston | 4 | 512 | 938 | 277 | 1450 | 5.23 | 362.5 |
| 8 | Temple | 4 | 483 | 856 | 242 | 1339 | 5.53 | 334.8 |
| 9 | South Florida | 4 | 632 | 704 | 280 | 1336 | 4.77 | 334.0 |
| 10 | Cincinnati | 3 | 495 | 766 | 186 | 1261 | 6.78 | 420.3 |
| 11 | Navy | 3 | 575 | 191 | 199 | 766 | 3.85 | 255.3 |