2021 Big Ten Conference Leaders All Purpose - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | A.J. Henning | Michigan | SO | WR | 4 | 43 | 17 | 108 | 67 | 17 | 235 | 13.8 | 58.8 |
| 2 | TJ Sheffield | Purdue | SO | WR | 4 | 0 | 111 | 48 | 70 | 25 | 229 | 9.2 | 57.3 |
| 3 | Raymond Niro III | N'western | JR | WR | 3 | -8 | 15 | 35 | 32 | 7 | 74 | 10.6 | 24.7 |
| 4 | Jaxon Smith-Njigba | Ohio State | SO | WR | 4 | 0 | 724 | 32 | 0 | 48 | 756 | 15.8 | 189.0 |
| 5 | Jayden Reed | Mich St | JR | WR | 3 | 0 | 188 | 25 | 72 | 20 | 285 | 14.3 | 95.0 |
| 6 | Parker Washington | Penn State | SO | WR | 5 | 12 | 384 | 23 | 0 | 31 | 419 | 13.5 | 83.8 |
| 7 | Dean Engram | Wisconsin | SO | CB | 3 | 0 | 0 | 22 | 0 | 4 | 22 | 5.5 | 7.3 |
| 8 | Tarheeb Still | Maryland | SO | DB | 4 | 0 | 0 | 21 | 0 | 7 | 29 | 4.1 | 7.3 |
| 9 | Bryce Kirtz | N'western | SO | WR | 1 | 0 | 80 | 13 | 0 | 8 | 93 | 11.6 | 93.0 |
| 10 | Aron Cruickshank | Rutgers | JR | WR | 3 | 0 | 172 | 12 | 130 | 22 | 314 | 14.3 | 104.7 |
| 11 | Jahan Dotson | Penn State | SR | WR | 4 | 8 | 373 | 10 | 0 | 40 | 391 | 9.8 | 97.8 |
| 11 | JJ Jefferson | N'western | SR | WR | 2 | 0 | 4 | 10 | 0 | 3 | 14 | 4.7 | 7.0 |
| 13 | Trey Potts | Minnesota | SO | RB | 1 | 34 | 12 | 9 | 17 | 13 | 72 | 5.5 | 72.0 |
| 13 | Samori Toure | Nebraska | SR | WR | 5 | 19 | 323 | 9 | 0 | 26 | 351 | 13.5 | 70.2 |
| 15 | Jackson Anthrop | Purdue | SR | WR | 4 | 40 | 240 | 4 | 11 | 32 | 295 | 9.2 | 73.8 |
| 16 | Oliver Martin | Nebraska | JR | WR | 3 | 0 | 39 | 2 | 0 | 3 | 41 | 13.7 | 13.7 |