2021 Big Ten Conference Leaders Interceptions - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Ji'Ayir Brown | Penn State | SR | S | 1 | 2 | 0 | 0 | 2.00 |
| 1 | Jermari Harris | Iowa | SO | DB | 2 | 2 | 0 | 0 | 1.00 |
| 3 | Cal Haladay | Mich St | FR | LB | 1 | 1 | 78 | 1 | 1.00 |
| 3 | Michael Dixon | Minnesota | SO | DB | 1 | 1 | 0 | 0 | 1.00 |
| 3 | John Torchio | Wisconsin | JR | S | 1 | 1 | 0 | 0 | 1.00 |
| 3 | Jack Campbell | Iowa | JR | LB | 2 | 1 | 1 | 0 | 0.50 |
| 3 | Caden Kolesar | Michigan | JR | DB | 2 | 1 | 1 | 0 | 0.50 |