2021 Big Ten Conference Leaders Total Defense - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Indiana | 1 | 218 | 102 | 69 | 320 | 4.64 | 320.0 |
| 2 | Wisconsin | 4 | 287 | 655 | 234 | 942 | 4.03 | 235.5 |
| 3 | Ohio State | 4 | 334 | 716 | 264 | 1050 | 3.98 | 262.5 |
| 4 | Nebraska | 3 | 339 | 639 | 216 | 978 | 4.53 | 326.0 |
| 5 | Rutgers | 5 | 504 | 973 | 329 | 1477 | 4.49 | 295.4 |
| 6 | Iowa | 6 | 538 | 1212 | 407 | 1750 | 4.30 | 291.7 |
| 7 | Michigan State | 4 | 544 | 985 | 332 | 1529 | 4.61 | 382.3 |
| 8 | Michigan | 5 | 593 | 961 | 317 | 1554 | 4.90 | 310.8 |
| 9 | Purdue | 5 | 621 | 774 | 317 | 1395 | 4.40 | 279.0 |
| 10 | Minnesota | 7 | 674 | 888 | 391 | 1562 | 3.99 | 223.1 |
| 11 | Illinois | 5 | 722 | 1127 | 344 | 1849 | 5.38 | 369.8 |
| 12 | Penn State | 5 | 762 | 737 | 356 | 1499 | 4.21 | 299.8 |
| 13 | Maryland | 6 | 871 | 1312 | 410 | 2183 | 5.32 | 363.8 |
| 14 | Northwestern | 5 | 1097 | 1150 | 362 | 2247 | 6.21 | 449.4 |