2021 Big Ten Conference Leaders Scoring Defense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Penn State | 8 | 9 | 9 | 7 | 3 | 0 | 94 | 11.8 |
| 2 | Wisconsin | 10 | 15 | 7 | 13 | 0 | 0 | 124 | 12.4 |
| 3 | Michigan | 10 | 16 | 9 | 13 | 3 | 0 | 142 | 14.2 |
| 4 | Minnesota | 11 | 19 | 8 | 15 | 0 | 0 | 153 | 13.9 |
| 4 | Nebraska | 7 | 19 | 1 | 19 | 0 | 2 | 140 | 20.0 |
| 6 | Purdue | 9 | 20 | 10 | 19 | 0 | 0 | 169 | 18.8 |
| 7 | Ohio State | 9 | 21 | 7 | 20 | 0 | 0 | 167 | 18.6 |
| 7 | Maryland | 9 | 21 | 11 | 20 | 2 | 0 | 183 | 20.3 |
| 9 | Iowa | 12 | 23 | 16 | 21 | 0 | 0 | 207 | 17.3 |
| 10 | Michigan State | 10 | 25 | 15 | 22 | 1 | 0 | 219 | 21.9 |
| 11 | Rutgers | 9 | 26 | 4 | 24 | 0 | 0 | 192 | 21.3 |
| 12 | Illinois | 11 | 27 | 14 | 24 | 1 | 0 | 230 | 20.9 |
| 13 | Indiana | 7 | 30 | 5 | 29 | 0 | 0 | 224 | 32.0 |
| 14 | Northwestern | 9 | 32 | 13 | 29 | 0 | 0 | 260 | 28.9 |