2021 Big Ten Conference Leaders Total Offense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 10 | 2455 | 1571 | 673 | 4026 | 5.98 | 402.6 |
| 2 | Michigan | 10 | 2256 | 2119 | 702 | 4375 | 6.23 | 437.5 |
| 3 | Minnesota | 11 | 2182 | 1681 | 700 | 3863 | 5.52 | 351.2 |
| 4 | Illinois | 11 | 2019 | 1626 | 729 | 3645 | 5.00 | 331.4 |
| 5 | Michigan State | 10 | 1962 | 2582 | 668 | 4544 | 6.80 | 454.4 |
| 6 | Ohio State | 9 | 1836 | 3052 | 600 | 4888 | 8.15 | 543.1 |
| 7 | Nebraska | 7 | 1503 | 1923 | 493 | 3426 | 6.95 | 489.4 |
| 8 | Iowa | 12 | 1454 | 2135 | 780 | 3589 | 4.60 | 299.1 |
| 9 | Northwestern | 9 | 1381 | 1442 | 606 | 2823 | 4.66 | 313.7 |
| 10 | Maryland | 9 | 1339 | 2979 | 649 | 4318 | 6.65 | 479.8 |
| 11 | Rutgers | 9 | 1288 | 1407 | 611 | 2695 | 4.41 | 299.4 |
| 12 | Penn State | 8 | 969 | 2216 | 554 | 3185 | 5.75 | 398.1 |
| 13 | Indiana | 7 | 866 | 1370 | 475 | 2236 | 4.71 | 319.4 |
| 14 | Purdue | 9 | 800 | 3025 | 656 | 3825 | 5.83 | 425.0 |