2021 Big Ten Conference Leaders Sacks - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Michigan State | 10 | 36.0 | 259 | 3.60 |
| 2 | Ohio State | 9 | 33.0 | 234 | 3.67 |
| 3 | Wisconsin | 10 | 26.0 | 203 | 2.60 |
| 4 | Maryland | 9 | 25.0 | 189 | 2.78 |
| 5 | Minnesota | 11 | 25.0 | 184 | 2.27 |
| 6 | Illinois | 11 | 29.0 | 179 | 2.64 |
| 7 | Iowa | 12 | 24.0 | 167 | 2.00 |
| 8 | Michigan | 10 | 26.0 | 153 | 2.60 |
| 9 | Penn State | 8 | 17.0 | 144 | 2.13 |
| 10 | Rutgers | 9 | 19.0 | 124 | 2.11 |
| 11 | Purdue | 9 | 17.0 | 118 | 1.89 |
| 12 | Nebraska | 7 | 12.0 | 87 | 1.71 |
| 13 | Northwestern | 9 | 14.0 | 80 | 1.56 |
| 14 | Indiana | 7 | 7.0 | 54 | 1.00 |