2021 Mid-American Conference Leaders Long All Purpose Plays - Games vs. FBS Teams With Winning Record Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Bryant Koback | Toledo | JR | RB | 6 | 7 | 4 | 3 | 3 | 1 | 0 | 0 |
| 1 | Kalil Pimpleton | CMU | JR | WR | 6 | 8 | 7 | 4 | 3 | 3 | 1 | 1 |
| 3 | Justin Hall | Ball State | SR | WR | 8 | 8 | 2 | 2 | 2 | 2 | 1 | 1 |
| 3 | Matt Landers | Toledo | JR | WR | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 1 |
| 3 | Lew Nichols III | CMU | FR | RB | 6 | 6 | 2 | 2 | 2 | 0 | 0 | 0 |
| 3 | Sean Tyler | W Mich | SO | RB | 7 | 3 | 2 | 2 | 2 | 2 | 1 | 1 |
| 7 | Keshunn Abram | Kent State | SR | WR | 9 | 4 | 4 | 2 | 1 | 1 | 0 | 0 |
| 7 | Hassan Beydoun | EMU | JR | WR | 7 | 4 | 2 | 1 | 1 | 0 | 0 | 0 |
| 7 | David Carter Jr. | EMU | FR | DB | 7 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 7 | Dante Cephas | Kent State | SO | WR | 9 | 6 | 6 | 2 | 1 | 1 | 1 | 0 |
| 7 | Corey Crooms | W Mich | SO | WR | 7 | 5 | 3 | 3 | 1 | 1 | 0 | 0 |
| 7 | Kevin Davis | Miami (Oh) | FR | RB | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 7 | Jawon Hamilton | EMU | SR | RB | 5 | 3 | 1 | 1 | 1 | 0 | 0 | 0 |
| 7 | Marion Lukes | CMU | FR | RB | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 7 | Devin Maddox | Toledo | SO | WR | 6 | 3 | 1 | 1 | 1 | 0 | 0 | 0 |
| 7 | Michael Mathison | Akron | SO | WR | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 7 | Jalen McGaughy | Ball State | SO | WR | 8 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 7 | Bryce Mitchell | Toledo | SR | WR | 4 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 7 | Skyy Moore | W Mich | SO | WR | 7 | 4 | 2 | 2 | 1 | 1 | 0 | 0 |
| 7 | Jonzell Norrils | Akron | FR | RB | 3 | 2 | 2 | 2 | 1 | 1 | 0 | 0 |
| 7 | Cameron Odom | Ohio | SR | WR | 5 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 7 | Clint Ratkovich | N Illinois | SR | RB | 7 | 2 | 2 | 2 | 1 | 1 | 1 | 1 |
| 7 | Trayvon Rudolph | N Illinois | FR | WR | 7 | 7 | 4 | 1 | 1 | 1 | 0 | 0 |
| 7 | Terion Stewart | BGSU | FR | RB | 5 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 7 | Jacquez Stuart | Toledo | FR | RB | 6 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 7 | Devontez Walker | Kent State | FR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 7 | Harrison Waylee | N Illinois | FR | RB | 3 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 7 | Xavier Williams | Kent State | SR | RB | 8 | 3 | 2 | 2 | 1 | 1 | 0 | 0 |