2021 Mid-American Conference Leaders Long All Purpose Plays - Games Lost Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Bryant Koback | Toledo | JR | RB | 6 | 7 | 4 | 3 | 3 | 1 | 0 | 0 |
| 1 | Jonzell Norrils | Akron | FR | RB | 9 | 3 | 3 | 3 | 2 | 2 | 0 | 0 |
| 3 | Dante Cephas | Kent State | SO | WR | 7 | 4 | 4 | 2 | 1 | 1 | 1 | 0 |
| 3 | Matt Landers | Toledo | JR | WR | 6 | 2 | 2 | 2 | 2 | 2 | 2 | 1 |
| 3 | Michael Mathison | Akron | SO | WR | 9 | 6 | 2 | 2 | 1 | 1 | 1 | 1 |
| 3 | Clint Ratkovich | N Illinois | SR | RB | 5 | 2 | 2 | 2 | 1 | 1 | 1 | 1 |
| 3 | Armani Rogers | Ohio | SR | QB | 9 | 2 | 2 | 2 | 1 | 1 | 1 | 1 |
| 8 | Keshunn Abram | Kent State | SR | WR | 7 | 3 | 3 | 1 | 0 | 0 | 0 | 0 |
| 8 | Bryan Bradford | Kent State | SO | RB | 6 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 8 | David Carter Jr. | EMU | FR | DB | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 8 | Ron Cook, Jr. | Buffalo | JR | RB | 8 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 8 | Corey Crooms | W Mich | SO | WR | 5 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 8 | Kevin Davis | Miami (Oh) | FR | RB | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 8 | Jay Ducker | N Illinois | FR | RB | 5 | 3 | 2 | 1 | 0 | 0 | 0 | 0 |
| 8 | Jhaylin Embry | BGSU | FR | WR | 8 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 8 | Justin Hall | Ball State | SR | WR | 5 | 4 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Jayshon Jackson | Ball State | JR | WR | 7 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 8 | Dominic Johnson | Buffalo | SR | WR | 8 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 8 | Nykeim Johnson | Kent State | SR | WR | 7 | 3 | 1 | 1 | 0 | 0 | 0 | 0 |
| 8 | Taron Keith | BGSU | FR | RB | 8 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 8 | Devin Maddox | Toledo | SO | WR | 6 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Bryce Mitchell | Toledo | SR | WR | 4 | 4 | 2 | 1 | 1 | 1 | 0 | 0 |
| 8 | Skyy Moore | W Mich | SO | WR | 5 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Kato Nelson | Akron | SR | QB | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 8 | Lew Nichols III | CMU | FR | RB | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Cameron Odom | Ohio | SR | WR | 9 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 8 | Kalil Pimpleton | CMU | JR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Ja'Shaun Poke | Kent State | JR | WR | 6 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 8 | Trayvon Rudolph | N Illinois | FR | WR | 5 | 9 | 3 | 1 | 1 | 1 | 0 | 0 |
| 8 | Christian Sims | BGSU | JR | TE | 7 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 8 | Jack Sorenson | Miami (Oh) | SR | WR | 6 | 5 | 2 | 1 | 1 | 1 | 1 | 0 |
| 8 | Terion Stewart | BGSU | FR | RB | 6 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 8 | Jacquez Stuart | Toledo | FR | RB | 6 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 8 | JaCorey Sullivan | CMU | SR | WR | 4 | 3 | 2 | 1 | 1 | 1 | 0 | 0 |
| 8 | De'Montre Tuggle | Ohio | SR | RB | 9 | 3 | 1 | 1 | 1 | 1 | 1 | 0 |
| 8 | Devontez Walker | Kent State | FR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Jalen Walker | Miami (Oh) | JR | WR | 6 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 8 | Harrison Waylee | N Illinois | FR | RB | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 8 | Andre Williams | Akron | JR | WR | 8 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |