2021 Mid-American Conference Leaders Passes Defended - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Charles Amankwaa | Akron | JR | DB | 1 | 1 | 1 | 2 | 2.00 |
| 1 | Chris McDonald | Toledo | SO | CB | 1 | 1 | 1 | 2 | 2.00 |
| 1 | Quinyon Mitchell | Toledo | FR | CB | 1 | 0 | 2 | 2 | 2.00 |
| 1 | Jamal Hines | Toledo | JR | OLB | 1 | 0 | 2 | 2 | 2.00 |
| 1 | Ralph Holley | W Mich | SR | DL | 2 | 0 | 2 | 2 | 1.00 |
| 6 | Sterling Weatherford | Miami (Oh) | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 6 | John Saunders Jr. | Miami (Oh) | FR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 6 | Alvin Floyd | Ohio | SR | S | 1 | 1 | 0 | 1 | 1.00 |
| 6 | Elvis Hines | Kent State | SR | CB | 1 | 0 | 1 | 1 | 1.00 |
| 6 | Capone Blue | Kent State | JR | CB | 1 | 0 | 1 | 1 | 1.00 |
| 6 | Jordan Gandy | N Illinois | SO | CB | 1 | 0 | 1 | 1 | 1.00 |
| 6 | Kai Caesar | Ohio | SR | DT | 1 | 0 | 1 | 1 | 1.00 |
| 6 | Will Evans | Ohio | SR | DE | 1 | 0 | 1 | 1 | 1.00 |
| 6 | Dorian Jackson | W Mich | JR | CB | 2 | 1 | 0 | 1 | 0.50 |
| 6 | Harrison Taylor | W Mich | JR | LB | 2 | 0 | 1 | 1 | 0.50 |
| 6 | Therran Coleman | W Mich | SR | CB | 2 | 0 | 1 | 1 | 0.50 |