2021 Mid-American Conference Leaders First Downs - Games in August/September Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Kent State | 4 | 53 | 30 | 11 | 94 | 23.5 |
| 1 | Eastern Michigan | 4 | 39 | 39 | 11 | 89 | 22.3 |
| 3 | Western Michigan | 4 | 32 | 45 | 10 | 87 | 21.8 |
| 3 | Ball State | 4 | 29 | 36 | 10 | 75 | 18.8 |
| 5 | Buffalo | 4 | 43 | 34 | 9 | 86 | 21.5 |
| 5 | Miami (Ohio) | 4 | 28 | 40 | 9 | 77 | 19.3 |
| 7 | Central Michigan | 4 | 44 | 50 | 7 | 101 | 25.3 |
| 7 | Akron | 4 | 27 | 45 | 7 | 79 | 19.8 |
| 7 | Ohio | 4 | 28 | 33 | 7 | 68 | 17.0 |
| 7 | Toledo | 4 | 28 | 32 | 7 | 67 | 16.8 |
| 11 | Bowling Green | 4 | 15 | 34 | 6 | 55 | 13.8 |
| 12 | Northern Illinois | 4 | 39 | 34 | 5 | 78 | 19.5 |