2021 Mid-American Conference Leaders Sacks - Games in August/September Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Western Michigan | 4 | 16.0 | 113 | 4.00 |
| 2 | Buffalo | 4 | 12.0 | 89 | 3.00 |
| 3 | Bowling Green | 4 | 12.0 | 82 | 3.00 |
| 4 | Central Michigan | 4 | 8.0 | 72 | 2.00 |
| 5 | Toledo | 4 | 12.0 | 71 | 3.00 |
| 5 | Eastern Michigan | 4 | 10.0 | 71 | 2.50 |
| 7 | Akron | 4 | 5.0 | 60 | 1.25 |
| 8 | Miami (Ohio) | 4 | 7.0 | 55 | 1.75 |
| 9 | Ball State | 4 | 9.0 | 52 | 2.25 |
| 10 | Ohio | 4 | 3.0 | 35 | 0.75 |
| 11 | Northern Illinois | 4 | 5.0 | 32 | 1.25 |
| 12 | Kent State | 4 | 5.0 | 19 | 1.25 |