2021 Mid-American Conference Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Eastern Michigan | 11 | 74 | 161 | 24 | 259 | 23.5 |
| 2 | Miami (Ohio) | 11 | 83 | 130 | 21 | 234 | 21.3 |
| 3 | Central Michigan | 9 | 94 | 108 | 10 | 212 | 23.6 |
| 3 | Ball State | 11 | 83 | 108 | 17 | 208 | 18.9 |
| 5 | Western Michigan | 10 | 127 | 106 | 21 | 254 | 25.4 |
| 5 | Toledo | 12 | 119 | 106 | 24 | 249 | 20.8 |
| 7 | Kent State | 10 | 144 | 105 | 19 | 268 | 26.8 |
| 8 | Buffalo | 10 | 115 | 99 | 22 | 236 | 23.6 |
| 9 | Northern Illinois | 11 | 152 | 94 | 21 | 267 | 24.3 |
| 10 | Akron | 9 | 71 | 91 | 10 | 172 | 19.1 |
| 11 | Bowling Green | 9 | 54 | 79 | 10 | 143 | 15.9 |
| 12 | Ohio | 9 | 95 | 71 | 24 | 190 | 21.1 |