2021 Pac-12 Conference Leaders Interceptions - Games in August/September Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Bennett Williams | Oregon | JR | S | 4 | 3 | 92 | 1 | 0.75 |
| 2 | Merlin Robertson | Ariz St | SR | LB | 4 | 1 | 60 | 0 | 0.25 |
| 3 | Clark Phillips III | Utah | FR | CB | 4 | 1 | 54 | 1 | 0.25 |
| 4 | Greg Johnson | USC | SR | S | 4 | 1 | 37 | 1 | 0.25 |
| 5 | Christian Roland-Wallace | Arizona | SO | CB | 4 | 1 | 36 | 0 | 0.25 |
| 5 | Derrick Langford Jr. | Wash St | SR | DB | 4 | 1 | 36 | 0 | 0.25 |
| 7 | Julius Irvin | Washington | SO | DB | 3 | 1 | 34 | 0 | 0.33 |
| 7 | DeAndre Pierce | Ariz St | SR | DB | 4 | 1 | 34 | 0 | 0.25 |
| 7 | Caleb Johnson | UCLA | SR | LB | 4 | 1 | 34 | 0 | 0.25 |
| 10 | Kenny Churchwell III | UCLA | JR | DB | 4 | 1 | 33 | 0 | 0.25 |
| 11 | Kyu Blu Kelly | Stanford | JR | CB | 4 | 2 | 31 | 1 | 0.50 |
| 12 | Daniel Isom | Wash St | SR | DB | 4 | 1 | 27 | 0 | 0.25 |
| 13 | Skyler Thomas | Oregon St | FR | DB | 4 | 1 | 26 | 0 | 0.25 |
| 14 | Jack Colletto | Oregon St | JR | ILB | 3 | 1 | 19 | 0 | 0.33 |
| 15 | Alex Austin | Oregon St | FR | DB | 4 | 1 | 17 | 0 | 0.25 |
| 16 | Kenny Hebert | Arizona | SR | LB | 4 | 1 | 16 | 0 | 0.25 |
| 17 | Jayden Williams | USC | JR | CB | 4 | 1 | 14 | 0 | 0.25 |
| 18 | Karene Reid | Utah | FR | LB | 3 | 1 | 13 | 0 | 0.33 |
| 19 | Datona Jackson | UCLA | SR | DL | 4 | 1 | 11 | 0 | 0.25 |
| 20 | Drake Jackson | USC | JR | OLB | 4 | 1 | 9 | 0 | 0.25 |
| 21 | Daniel Scott | California | SR | S | 4 | 2 | 8 | 1 | 0.50 |
| 22 | Nate Heaukulani | Oregon | SR | ILB | 4 | 1 | 7 | 0 | 0.25 |
| 23 | Jimmy Wyrick | Stanford | FR | CB | 3 | 1 | 6 | 0 | 0.33 |
| 24 | Justus Rogers | Wash St | SR | LB | 4 | 1 | 5 | 0 | 0.25 |
| 25 | Jay Shaw | UCLA | SR | DB | 4 | 1 | 3 | 0 | 0.25 |
| 26 | Verone McKinley III | Oregon | SO | S | 4 | 4 | 1 | 0 | 1.00 |
| 26 | Alton Julian | Oregon St | SO | DB | 4 | 1 | 1 | 0 | 0.25 |