2021 Pac-12 Conference Leaders Rushing Defense - Games in October Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | California | 4 | 128 | 492 | 3.84 | 3 | 32.00 | 123.00 |
| 2 | Oregon | 4 | 146 | 506 | 3.47 | 5 | 36.50 | 126.50 |
| 3 | USC | 4 | 147 | 557 | 3.79 | 9 | 36.75 | 139.25 |
| 4 | Arizona State | 4 | 150 | 585 | 3.90 | 6 | 37.50 | 146.25 |
| 5 | UCLA | 5 | 174 | 793 | 4.56 | 14 | 34.80 | 158.60 |
| 6 | Utah | 4 | 136 | 646 | 4.75 | 6 | 34.00 | 161.50 |
| 7 | Washington State | 5 | 194 | 871 | 4.49 | 9 | 38.80 | 174.20 |
| 8 | Oregon State | 4 | 147 | 711 | 4.84 | 7 | 36.75 | 177.75 |
| 9 | Washington | 4 | 158 | 764 | 4.84 | 6 | 39.50 | 191.00 |
| 10 | Arizona | 4 | 168 | 768 | 4.57 | 5 | 42.00 | 192.00 |
| 11 | Stanford | 4 | 167 | 812 | 4.86 | 8 | 41.75 | 203.00 |
| 12 | Colorado | 4 | 142 | 814 | 5.73 | 5 | 35.50 | 203.50 |