2021 Independent Leaders Rushing Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Notre Dame | 3 | 115 | 383 | 3.33 | 2 | 38.33 | 127.67 |
| 2 | BYU | 5 | 207 | 714 | 3.45 | 8 | 41.40 | 142.80 |
| 3 | Army | 9 | 278 | 919 | 3.31 | 10 | 30.89 | 102.11 |
| 4 | Liberty | 10 | 410 | 1363 | 3.32 | 14 | 41.00 | 136.30 |
| 5 | New Mexico State | 9 | 325 | 1778 | 5.47 | 19 | 36.11 | 197.56 |
| 5 | Connecticut | 7 | 317 | 1587 | 5.01 | 19 | 45.29 | 226.71 |
| 7 | Massachusetts | 7 | 285 | 1662 | 5.83 | 24 | 40.71 | 237.43 |