2021 Independent Leaders Passes Defended - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Notre Dame | 11 | 15 | 32 | 47 | 4.27 |
| 2 | Army | 12 | 10 | 36 | 46 | 3.83 |
| 3 | Liberty | 11 | 9 | 36 | 45 | 4.09 |
| 4 | BYU | 10 | 11 | 31 | 42 | 4.20 |
| 5 | Connecticut | 10 | 8 | 32 | 40 | 4.00 |
| 6 | Massachusetts | 11 | 2 | 32 | 34 | 3.09 |
| 7 | New Mexico State | 8 | 7 | 18 | 25 | 3.13 |