2021 Independent Leaders Passes Defended - Games in August/September Only through 01/10/2022
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Army | 4 | 4 | 17 | 21 | 5.25 |
| 2 | Notre Dame | 4 | 9 | 16 | 25 | 6.25 |
| 2 | Connecticut | 5 | 3 | 16 | 19 | 3.80 |
| 4 | Massachusetts | 4 | 0 | 15 | 15 | 3.75 |
| 5 | New Mexico State | 5 | 7 | 13 | 20 | 4.00 |
| 5 | BYU | 4 | 4 | 13 | 17 | 4.25 |
| 5 | Liberty | 4 | 2 | 13 | 15 | 3.75 |