2021 National Leaders Interceptions - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Erick Hallett II | Pittsburgh | JR | DB | 3 | 2 | 19 | 1 | 0.67 |
| 1 | Al Walcott | Baylor | JR | CB | 5 | 2 | 96 | 1 | 0.40 |
| 1 | Christopher Smith | Georgia | SR | DB | 5 | 2 | 74 | 1 | 0.40 |
| 1 | John Saunders Jr. | Miami (Oh) | FR | DB | 1 | 1 | 32 | 1 | 1.00 |
| 1 | Chris McDonald | Toledo | SO | CB | 1 | 1 | 27 | 1 | 1.00 |
| 1 | Keondre Swoopes | UAB | JR | S | 2 | 1 | 61 | 1 | 0.50 |
| 1 | Kenyon Reed | SJSU | SO | CB | 2 | 1 | 58 | 1 | 0.50 |
| 1 | Malik Dixon | UConn | FR | DB | 2 | 1 | 37 | 1 | 0.50 |
| 1 | Jermaine Waller | Va Tech | JR | DB | 2 | 1 | 26 | 1 | 0.50 |
| 1 | Cal Haladay | Mich St | FR | LB | 3 | 1 | 78 | 1 | 0.33 |
| 1 | SirVocea Dennis | Pittsburgh | JR | LB | 3 | 1 | 50 | 1 | 0.33 |
| 1 | Justin Wright | Tulsa | JR | LB | 4 | 1 | 55 | 1 | 0.25 |
| 1 | Riko Jeffers | Texas Tech | SR | LB | 4 | 1 | 13 | 1 | 0.25 |
| 1 | Alontae Taylor | Tennessee | SR | DB | 5 | 1 | 56 | 1 | 0.20 |
| 1 | Jordan Battle | Alabama | JR | DB | 5 | 1 | 42 | 1 | 0.20 |
| 1 | Devin Lloyd | Utah | JR | LB | 5 | 1 | 34 | 1 | 0.20 |
| 1 | Daequan Hardy | Penn State | SO | CB | 5 | 1 | 17 | 1 | 0.20 |
| 1 | Kelee Ringo | Georgia | FR | DB | 6 | 1 | 79 | 1 | 0.17 |