2021 Louisville Cardinals Rushing through 01/10/2022
| Name | Yr | Pos | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Malik Cunningham | JR | QB | 13 | 173 | 1034 | 5.98 | 20 | 13.31 | 79.54 |
| 2 | Jalen Mitchell | FR | RB | 12 | 155 | 722 | 4.66 | 5 | 12.92 | 60.17 |
| 3 | Trevion Cooley | FR | RB | 12 | 86 | 431 | 5.01 | 1 | 7.17 | 35.92 |
| 4 | Hassan Hall | JR | RB | 9 | 38 | 272 | 7.16 | 1 | 4.22 | 30.22 |
| 5 | Maurice Burkley | SR | RB | 13 | 22 | 102 | 4.64 | 1 | 1.69 | 7.85 |
| 6 | Jawhar Jordan | FR | RB | 4 | 14 | 94 | 6.71 | 0 | 3.50 | 23.50 |
| 7 | K.J. Cloyd | SO | LB | 13 | 1 | 55 | 55.00 | 0 | 0.08 | 4.23 |
| 8 | Aidan Robbins | FR | RB | 4 | 2 | 41 | 20.50 | 1 | 0.50 | 10.25 |
| 9 | Evan Conley | SO | QB | 5 | 3 | 26 | 8.67 | 0 | 0.60 | 5.20 |
| 10 | Ahmari Huggins-Bruce | FR | WR | 12 | 2 | 15 | 7.50 | 0 | 0.17 | 1.25 |
| 11 | Brock Domann | SO | QB | 1 | 2 | 5 | 2.50 | 0 | 2.00 | 5.00 |
| 12 | Braden Smith | SO | WR | 5 | 1 | 3 | 3.00 | 0 | 0.20 | 0.60 |
| 13 | Victoine Brown | FR | DL | 4 | 2 | -4 | -2.00 | 0 | 0.50 | -1.00 |
| 14 | Team | 12 | 4 | -5 | -1.25 | 0 | 0.33 | -0.42 | ||
| 15 | Shai Werts | SR | WR | 8 | 2 | -9 | -4.50 | 0 | 0.25 | -1.13 |
| 16 | Kei'Trel Clark | SO | DB | 9 | 1 | -14 | -14.00 | 0 | 0.11 | -1.56 |
| Total | 13 | 508 | 2768 | 5.45 | 29 | 39.08 | 212.92 | |||
| Opponents | 13 | 467 | 2037 | 4.36 | 23 | 35.92 | 156.69 |