2022 Conference USA Leaders Rushing Defense - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Rice | 5 | 143 | 980 | 6.85 | 9 | 28.60 | 196.00 |
| 2 | UTEP | 4 | 142 | 718 | 5.06 | 8 | 35.50 | 179.50 |
| 3 | Middle Tennessee | 5 | 183 | 427 | 2.33 | 2 | 36.60 | 85.40 |
| 4 | Western Kentucky | 6 | 225 | 802 | 3.56 | 8 | 37.50 | 133.67 |
| 5 | UAB | 5 | 190 | 879 | 4.63 | 11 | 38.00 | 175.80 |
| 6 | Florida Atlantic | 4 | 155 | 677 | 4.37 | 6 | 38.75 | 169.25 |
| 7 | Florida International | 4 | 157 | 724 | 4.61 | 8 | 39.25 | 181.00 |
| 8 | Louisiana Tech | 4 | 161 | 922 | 5.73 | 10 | 40.25 | 230.50 |
| 9 | Charlotte | 4 | 170 | 1050 | 6.18 | 14 | 42.50 | 262.50 |
| 10 | North Texas | 5 | 224 | 1245 | 5.56 | 14 | 44.80 | 249.00 |
| 11 | UTSA | 5 | 228 | 894 | 3.92 | 10 | 45.60 | 178.80 |