2022 Conference USA Leaders Opponent First Downs - Games in August/September Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | UAB | 3 | 22 | 31 | 4 | 57 | 19.0 |
| 2 | Florida International | 3 | 30 | 45 | 6 | 81 | 27.0 |
| 3 | Louisiana Tech | 4 | 52 | 35 | 7 | 94 | 23.5 |
| 4 | Western Kentucky | 4 | 32 | 37 | 8 | 77 | 19.3 |
| 5 | Rice | 4 | 28 | 32 | 9 | 69 | 17.3 |
| 5 | UTSA | 5 | 45 | 51 | 9 | 105 | 21.0 |
| 5 | North Texas | 5 | 52 | 57 | 9 | 118 | 23.6 |
| 8 | UTEP | 5 | 48 | 36 | 11 | 95 | 19.0 |
| 9 | Middle Tennessee | 5 | 41 | 64 | 14 | 119 | 23.8 |
| 10 | Charlotte | 5 | 58 | 66 | 15 | 139 | 27.8 |
| 11 | Florida Atlantic | 5 | 34 | 54 | 16 | 104 | 20.8 |