2022 Conference USA Leaders First Downs - Games in August/September Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | UTSA | 5 | 45 | 83 | 8 | 136 | 27.2 |
| 2 | Western Kentucky | 4 | 32 | 57 | 11 | 100 | 25.0 |
| 3 | Florida Atlantic | 5 | 50 | 57 | 14 | 121 | 24.2 |
| 4 | North Texas | 5 | 50 | 58 | 12 | 120 | 24.0 |
| 5 | Rice | 4 | 35 | 44 | 10 | 89 | 22.3 |
| 6 | Charlotte | 5 | 31 | 59 | 14 | 104 | 20.8 |
| 7 | UAB | 3 | 32 | 21 | 8 | 61 | 20.3 |
| 8 | UTEP | 5 | 32 | 55 | 12 | 99 | 19.8 |
| 9 | Louisiana Tech | 4 | 24 | 39 | 12 | 75 | 18.8 |
| 10 | Florida International | 3 | 12 | 36 | 7 | 55 | 18.3 |
| 11 | Middle Tennessee | 5 | 26 | 49 | 12 | 87 | 17.4 |