2022 Conference USA Leaders Passes Defended - Games in November Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Middle Tennessee | 4 | 6 | 37 | 43 | 10.75 |
| 2 | Florida Atlantic | 3 | 4 | 22 | 26 | 8.67 |
| 3 | UTSA | 4 | 7 | 20 | 27 | 6.75 |
| 4 | UAB | 4 | 1 | 19 | 20 | 5.00 |
| 5 | Western Kentucky | 4 | 6 | 12 | 18 | 4.50 |
| 6 | Louisiana Tech | 4 | 4 | 12 | 16 | 4.00 |
| 7 | UTEP | 3 | 2 | 9 | 11 | 3.67 |
| 8 | Charlotte | 3 | 3 | 7 | 10 | 3.33 |
| 9 | Rice | 4 | 2 | 11 | 13 | 3.25 |
| 10 | North Texas | 3 | 3 | 5 | 8 | 2.67 |
| 11 | Florida International | 4 | 2 | 8 | 10 | 2.50 |