2022 Big 12 Conference Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Dylan Horton | TCU | SR | DL | 5 | 7.0 | 60 | 1.40 |
| 2 | Tyree Wilson | Texas Tech | SR | OLB | 3 | 3.0 | 23 | 1.00 |
| 3 | Will McDonald IV | Iowa State | SR | DE | 3 | 2.0 | 16 | 0.67 |
| 3 | Lonnie Phelps | Kansas | JR | DE | 3 | 2.0 | 12 | 0.67 |
| 5 | Barryn Sorrell | Texas | SO | EDG | 4 | 2.5 | 25 | 0.63 |
| 5 | Jared Bartlett | WVU | SO | BAN | 4 | 2.5 | 25 | 0.63 |
| 7 | Tony Bradford Jr. | Texas Tech | SR | DL | 3 | 1.5 | 10 | 0.50 |
| 7 | Jesiah Pierre | Texas Tech | JR | OLB | 3 | 1.5 | 8 | 0.50 |
| 9 | Felix Anudike-Uzomah | Kansas St | JR | DE | 5 | 2.0 | 16 | 0.40 |
| 9 | Daniel Green | Kansas St | SR | LB | 5 | 2.0 | 12 | 0.40 |
| 11 | Dante Stills | WVU | SR | DL | 4 | 1.5 | 17 | 0.38 |
| 11 | Danny Stutsman | Oklahoma | SO | LB | 4 | 1.5 | 11 | 0.38 |
| 11 | Ovie Oghoufo | Texas | SR | EDG | 4 | 1.5 | 6 | 0.38 |
| 14 | Al Walcott | Baylor | SR | S | 3 | 1.0 | 17 | 0.33 |
| 14 | Gabe Hall | Baylor | JR | DL | 3 | 1.0 | 10 | 0.33 |
| 14 | TJ Franklin | Baylor | SR | DL | 3 | 1.0 | 9 | 0.33 |
| 14 | Bryson Jackson | Baylor | SR | OLB | 3 | 1.0 | 8 | 0.33 |
| 14 | Jaylon Hutchings | Texas Tech | SR | DL | 3 | 1.0 | 8 | 0.33 |
| 14 | Christian Morgan | Baylor | SR | S | 3 | 1.0 | 7 | 0.33 |
| 14 | Craig Young | Kansas | JR | LB | 3 | 1.0 | 5 | 0.33 |
| 14 | Tyler Lacy | Okla St | SR | DE | 3 | 1.0 | 4 | 0.33 |
| 14 | Dadrion Taylor-Demerson | Texas Tech | SR | DB | 3 | 1.0 | 3 | 0.33 |
| 14 | Davis Mallinger | WVU | FR | S | 3 | 1.0 | 3 | 0.33 |
| 14 | Trace Ford | Okla St | JR | DE | 3 | 1.0 | 1 | 0.33 |
| 25 | Jaylan Ford | Texas | JR | LB | 4 | 1.0 | 11 | 0.25 |
| 25 | Ryan Watts | Texas | JR | DB | 4 | 1.0 | 10 | 0.25 |
| 25 | Jordan Jefferson | WVU | JR | DL | 4 | 1.0 | 7 | 0.25 |
| 25 | Sean Martin | WVU | SO | DL | 4 | 1.0 | 6 | 0.25 |
| 25 | Lee Kpogba | WVU | JR | LB | 4 | 1.0 | 6 | 0.25 |
| 25 | Diamonte Tucker-Dorsey | Texas | SR | LB | 4 | 1.0 | 5 | 0.25 |
| 25 | Keondre Coburn | Texas | SR | DL | 4 | 1.0 | 2 | 0.25 |
| 32 | Nate Matlack | Kansas St | SO | DE | 5 | 1.0 | 13 | 0.20 |
| 32 | Dee Winters | TCU | SR | LB | 5 | 1.0 | 12 | 0.20 |
| 32 | Robert Hentz II | Kansas St | SR | NG | 5 | 1.0 | 10 | 0.20 |
| 32 | Tymon Mitchell | TCU | JR | DL | 5 | 1.0 | 7 | 0.20 |
| 32 | VJ Payne | Kansas St | FR | S | 5 | 1.0 | 4 | 0.20 |
| 32 | Austin Moore | Kansas St | JR | LB | 5 | 1.0 | 3 | 0.20 |
| 38 | Garmon Randolph | Baylor | JR | OLB | 3 | 0.5 | 4 | 0.17 |
| 38 | DeMarvion Overshown | Texas | SR | LB | 3 | 0.5 | 3 | 0.17 |
| 40 | Edward Vesterinen | WVU | SO | DL | 4 | 0.5 | 6 | 0.13 |
| 40 | Trey Morrison | Oklahoma | SR | DB | 4 | 0.5 | 5 | 0.13 |
| 40 | Jasir Cox | WVU | SR | SPR | 4 | 0.5 | 5 | 0.13 |
| 40 | Isaiah Coe | Oklahoma | JR | DL | 4 | 0.5 | 3 | 0.13 |
| 40 | Josh Ellison | Oklahoma | SR | DL | 4 | 0.5 | 3 | 0.13 |
| 40 | Moro Ojomo | Texas | SR | DL | 4 | 0.5 | 3 | 0.13 |
Note: To qualify, player must have played in 75% of his team's games.