2022 Big 12 Conference Leaders Sacks - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Reggie Grimes II | Oklahoma | JR | DL | 2 | 4.0 | 31 | 2.00 |
| 2 | Matt Jones | Baylor | JR | LB | 3 | 1.5 | 15 | 0.50 |
| 2 | Barryn Sorrell | Texas | SO | EDG | 2 | 1.5 | 14 | 0.75 |
| 2 | Ethan Downs | Oklahoma | SO | DL | 2 | 1.5 | 5 | 0.75 |
| 5 | Myles Mendeszoon | Iowa State | FR | LB | 1 | 1.0 | 18 | 1.00 |
| 5 | Kosi Eldridge | Texas Tech | SR | LB | 1 | 1.0 | 15 | 1.00 |
| 5 | Joey Petersen | Iowa State | SO | DE | 1 | 1.0 | 12 | 1.00 |
| 5 | Will McDonald IV | Iowa State | SR | DE | 1 | 1.0 | 12 | 1.00 |
| 5 | Tyler Lacy | Okla St | SR | DE | 1 | 1.0 | 11 | 1.00 |
| 5 | David Ugwoegbu | Oklahoma | SR | LB | 2 | 1.0 | 10 | 0.50 |
| 5 | Brooks Miller | Baylor | SO | LB | 1 | 1.0 | 9 | 1.00 |
| 5 | Johnny Hodges | TCU | JR | LB | 1 | 1.0 | 9 | 1.00 |
| 5 | O'Rien Vance | Iowa State | SR | LB | 1 | 1.0 | 8 | 1.00 |
| 5 | Caleb Sampson | Kansas | SR | DL | 1 | 1.0 | 8 | 1.00 |
| 5 | Isaiah Coe | Oklahoma | JR | DL | 2 | 1.0 | 8 | 0.50 |
| 5 | Felix Anudike-Uzomah | Kansas St | JR | DE | 1 | 1.0 | 7 | 1.00 |
| 5 | Diamonte Tucker-Dorsey | Texas | SR | LB | 2 | 1.0 | 7 | 0.50 |
| 5 | Keondre Coburn | Texas | SR | DL | 2 | 1.0 | 6 | 0.50 |
| 5 | Danny Stutsman | Oklahoma | SO | LB | 2 | 1.0 | 5 | 0.50 |
| 5 | Collin Oliver | Okla St | SO | DE | 1 | 1.0 | 4 | 1.00 |
| 5 | Austin Moore | Kansas St | JR | LB | 1 | 1.0 | 3 | 1.00 |
| 5 | Taiwan Berryhill Jr. | Kansas | JR | LB | 1 | 1.0 | 3 | 1.00 |
| 5 | Tymon Mitchell | TCU | JR | DL | 1 | 1.0 | 3 | 1.00 |
| 5 | Craig Young | Kansas | JR | LB | 1 | 1.0 | 2 | 1.00 |
| 5 | Jereme Robinson | Kansas | JR | DL | 1 | 1.0 | 2 | 1.00 |
| 5 | Dimitri Moore | Texas Tech | SR | LB | 1 | 1.0 | 1 | 1.00 |
| 5 | Devin Neal | Baylor | JR | S | 2 | 1.0 | 1 | 0.50 |
| 28 | R Mason Thomas | Oklahoma | FR | DL | 2 | 0.5 | 5 | 0.25 |
| 28 | Moro Ojomo | Texas | SR | DL | 2 | 0.5 | 4 | 0.25 |
| 28 | TJ Franklin | Baylor | SR | DL | 3 | 0.5 | 4 | 0.17 |
| 28 | Jamoi Hodge | TCU | JR | LB | 1 | 0.5 | 2 | 0.50 |
| 28 | Dee Winters | TCU | SR | LB | 1 | 0.5 | 1 | 0.50 |