2022 Big 12 Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 3 | 180 | 523 | 174 | 703 | 4.04 | 234.3 |
| 2 | Baylor | 4 | 528 | 722 | 277 | 1250 | 4.51 | 312.5 |
| 3 | West Virginia | 3 | 193 | 599 | 170 | 792 | 4.66 | 264.0 |
| 4 | Oklahoma | 4 | 524 | 1001 | 303 | 1525 | 5.03 | 381.3 |
| 5 | Texas | 4 | 550 | 936 | 294 | 1486 | 5.05 | 371.5 |
| 6 | Oklahoma State | 4 | 592 | 912 | 294 | 1504 | 5.12 | 376.0 |
| 7 | Kansas State | 4 | 560 | 764 | 256 | 1324 | 5.17 | 331.0 |
| 8 | Texas Tech | 4 | 445 | 994 | 277 | 1439 | 5.19 | 359.8 |
| 9 | Kansas | 4 | 800 | 980 | 291 | 1780 | 6.12 | 445.0 |
| 10 | TCU | 5 | 742 | 1494 | 357 | 2236 | 6.26 | 447.2 |